49ers' Deebo Samuel's calf strain will keep him out for weeks.

[{"selector":"#anim-36f131bd-3c33-4a8b-80c6-1c60c2a0d8ab [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":3500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-37dccba0-6e07-4245-ab57-ffc0e434fe08","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] The 49ers will be without wide receiver Deebo Samuel for the next couple of weeks due to a calf strain.

[{"selector":"#anim-52e621de-aeb1-4827-8ac4-8bb178fb1ca6 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":3500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-95dc4cb3-b385-46a8-a825-22a149aab2d1","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] – Coach Kyle Shanahan announced Samuel's injury occurred late in Sunday's 23-17 loss to the Vikings.

[{"selector":"#anim-ba3ae9e7-4616-4bdf-88a2-880a73f6963d [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":3500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-5bd2ace5-368b-42de-9c10-7b0609a54044","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Samuel likely injured his calf on a play with about two minutes left in the game, after catching a pass under pressure.

[{"selector":"#anim-609daa16-9acc-4515-ad56-2d7c4c9a42b5 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":3500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-88ecd6a1-f0f0-45ce-8856-ba47a4f38140","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Despite the injury, Samuel finished with eight catches for 110 yards and two carries for -10 yards.

[{"selector":"#anim-1c445dd9-0fa5-4cf6-8716-31c4619e8d5d [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":3500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-a46d7a84-f438-4116-884e-bc67428ca6c5","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] With Samuel out, and Christian McCaffrey on IR, the Niners are missing two key offensive players.

[{"selector":"#anim-c7acda7c-207e-4579-ae13-bd794fa81fc1 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":3500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-e7fa2487-d681-41d6-8dec-3dce27b99dcf","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Samuel has a history of injuries, missing games with various issues since 2019, and has never played a full season.

[{"selector":"#anim-18abc6f0-31f9-4900-acff-2bdaab62426f [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":3500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-7c8bb856-0ea3-4cce-8f68-ffb79fa7860e","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] The 49ers’ active roster includes wideouts Brandon Aiyuk, Jauan Jennings, Jacob Cowing, Chris Conley, and Ronnie Bell.

[{"selector":"#anim-b7431404-4564-4529-a1eb-6da4ea2a50a8 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate(0%, 0%) scale(1.5)","translate(0%, 0%) scale(1)"]},"delay":0,"duration":3500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-db9d077f-7475-460f-b44f-0586150ea34a","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Shanahan praised Samuel’s performance before the injury, noting strong catches and a good game against the Jets.

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49ers' Deebo Samuel's calf strain will keep him out for weeks.

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